Afuco™ Anti-Human CD44 ADCC Therapeutic Antibody (RG7356), ADCC Enhanced
Anti-CD44 ADCC Enhanced Antibody (RG7356) is an ADCC enhanced antibody produced by our Afuco™ platform. RG7356 is a humanized antibody targeting the constant region of CD44 that shows antitumor efficacy in mice implanted with CD44-expressing tumors such as MDA-MB-231 breast cancer cells. Short-term treatment of tumor-bearing mice with RG7356 resulted in modifications of the MAPK pathway in the responsive model, although no effects on downstream phosphorylation were observed in a nonresponsive xenograft model.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-122CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | CD44 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | 4°C or -20°C, avoid repeated freezing and thawing. |