DOV-216303 free base
DOV-216303 free base is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD831 |
| CAS # | 66504-40-3 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | DOV-216303 free base; DOV 216,303 free base |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C11H11Cl2N |
| Exact Mass | 227.0269 |
| Molecular Weight | 228.116 |
| Elemental Analysis | C, 57.92; H, 4.86; Cl, 31.08; N, 6.14 |
| IUPAC/Chemical Name | 1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane |
| InChi Key | BSMNRYCSBFHEMQ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C11H11Cl2N/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11/h1-3,8,14H,4-6H2 |
| SMILES Code | ClC1=CC=C(C23CNCC2C3)C=C1Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |