ADL5859 HCl
ADL5859 is a potent, orally bioavailable delta opioid receptor agonist for the treatment of pain ( Ki of 0.8 nM ). ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD620 |
| CAS # | 850173-95-4 (ADL 5859 HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | ADL5859; ADL-5859; ADL 5859; ADL5859 HCl. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C24H29ClN2O3 |
| Molecular Weight | 428.957 |
| Elemental Analysis | C, 67.20; H, 6.81; Cl, 8.26; N, 6.53; O, 11.19 |
| IUPAC/Chemical Name | N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidin]-4-yl)benzamide hydrochloride |
| InChi Key | ZFNLSWREIULTDO-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C24H28N2O3.ClH/c1-3-26(4-2)23(28)18-10-8-17(9-11-18)19-16-24(12-14-25-15-13-24)29-21-7-5-6-20(27)22(19)21;/h5-11,16,25,27H,3-4,12-15H2,1-2H3;1H |
| SMILES Code | O=C(N(CC)CC)C1=CC=C(C2=CC3(CCNCC3)OC4=CC=CC(O)=C24)C=C1.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |