SB 202190, Free Base (FHPI, SB202190, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole, CAS 152121-30-7), >99%

LC Laboratories' Product Number S-1700 - SB 202190, Free Base (FHPI, SB202190, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole), >99% - for research use only. SB 202190, a pyridinyl imidazole, inhibits p38 kinase activity in vivo through competition with ATP. Induces apoptosis through activation of cysteine protease (CPP32)-like caspases. Blocks both lipopolysaccharide (LPS)-induced gene expression and nitric oxide (NO)-induced stabilization of interleukin (IL)-8 mRNA in monocytes.

• Supplier: LC Laboratories
• Product #: S-1700
• Sku #: S-1700_50mg