Ro 31-8220 mesylate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13866-10 mg |
| CAS # | 138489-18-6 |
| Pricing | 10 mg, USD $180.0 |
| Synonyms | Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate |
| MWt | 553.65 |
| Formula | C₂₆H₂₇N₅O₅S₂ |
| Biological Activity | Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. |
| Purity | ≥98.0% |