Lapaquistat acetate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16274-1 mg |
| CAS # | 189060-13-7 |
| Pricing | 1 mg, USD $160.0 |
| Synonyms | TAK-475 |
| MWt | 645.14 |
| Formula | C₃₃H₄₁ClN₂O₉ |
| Biological Activity | Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene[1]. Lapaquistat acetate (TAK-475) is originally intended use to Mevalonate Kinase Deficiency (MKD), it is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage[2]. |
| Purity | ≥99.0% |