anti-CD80 immunotoxin 6G7 (IgG)-Bouganin
This immunotoxin was achieved by conjugating/fusing the anti-CD80 monoclonal antibody to Bouganin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CD80-expressing cells. Once bind, the toxin enters cells by receptor-mediated endocytosis and enzymatically damages ribosomes, ultimately leading to cell death. It was designed for treatment of Hodgkin's disease or other CD80-expressing tumours.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AGTO-L001O |
| Pricing | Inquiry |
| Applications | This product is suitable for use in cytotoxicity assay, functional assay and immunotherapy. |
| Host | Mouse |
| Target | CD80 |
| Species Reactivity | Human |