Nutlin-3
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S1061 |
| Sku # | S1061-25mg |
| Pricing | 25mg, $370.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2022Quote: ... The cells were recovered for 3 days with further selection through nutlin treatment (10 uM, Selleck Chemicals S1061) for 5-7 days to enrich p53 KO cells ...
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bioRxiv - Cancer Biology 2020Quote: Nutlin 3 (Catalogue# S1061) was purchased from Selleck Chemicals LLC ...
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bioRxiv - Genetics 2023Quote: Nutlin-3 (Selleck Chemicals, S1061) was dissolved in DMSO at a stock concentration of 10 mM and used at a final concentration of 10 μM ...