Dynamin inhibitory peptide, myristoylated
| Supplier | Creative Peptides |
|---|---|
| Product # | R0848 |
| CAS # | 251634-22-7 |
| Pricing | Inquire |
| LabelingTarget | GTPase dynamin |
| MolecularFormula | C61H107N19O14 |
| MolecularWeight | 1330.64 |
| Sequence | Myr-QVPSRPNRAP-NH2 |
| Storage | -20°C |
| Explanation | Control peptide version of dynamin inhibitory peptide, myristoylated. It is an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. |
| Application | Cell-permeable version of dynamin inhibitory peptide , an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. |
| Activity | Inhibitor |
| InChI | InChI=1S/C61H107N19O14/c1-5-6-7-8-9-10-11-12-13-14-15-26-48(84)72-39(27-28-46(62)82)52(87)77-49(36(2)3)59(94)80-33-20-25-45(80)56(91)76-42(35-81)54(89)74-40(22-17-30-70-61(67)68)58(93)79-32-19-24-44(79)55(90)75-41(34-47(63)83)53(88)73-38(21-16-29-69-60(65)66)51(86)71-37(4)57(92)78-31-18-23-43(78)50(64)85/h36-45,49,81H,5-35H2,1-4H3,(H2,62,82)(H2,63,83)(H2,64,85)(H,71,86)(H,72,84)(H,73,88)(H,74,89)(H,75,90)(H,76,91)(H,77,87)(H4,65,66,69)(H4,67,68,70)/t37-,38-,39-,40-,41-,42-,43-,44-,45-,49-/m0/s1 |
| InChIKey | IFTSFTVOMZTNME-ZUSDHBTASA-N |
| IsomericSMILES | CCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N3CCC[C@H]3C(=O)N |
| Purity | >99 % |
| LongTermStorageConditions | -20 °C |