Importin-5 (IPO5) Antibody

IPO5 Antibody is a Rabbit Polyclonal antibody against IPO5. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Supplier Abbexa Ltd.
Product # abx001616-100UL
Pricing 100 µl USD $464.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB
UniProt Primary AC O00410
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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