BI-2852

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BI-2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells.

Supplier	Selleck Chemicals
Product #	S8959
Sku #	S8959-25mg
Pricing	25mg, $1170.00

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