Neural Cell Adhesion Molecule 1 / CD56 (NCAM1) Antibody
NCAM1 Antibody is a Rabbit Polyclonal antibody against NCAM1. Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronectin-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx000705-100UL |
| Pricing | 100 µl USD $507.5 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB, IHC |
| UniProt Primary AC | P13591 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |