CD11c (D1V9Y) Rabbit Antibody (BSA and Azide Free)

Supplier CD BioSciences
Product # AMA-0795
Pricing 100 µg, Inquire
Product Category Antibodies
Application WB, IHC, IF
Reactivity Mouse
Host Rabbit
Gene ID 16411
UniProt ID
Source/Isotype Rabbit IgG
MW (Target) 145 kDa
Storage Store at -20°C. Do not aliquot the antibody.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala1153 of mouse CD11c protein.
Background CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production. CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia.
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