AZD6482 (S-isomer)
This active molecular is the S-configuration isomer of AZD6482. AZD6482 is a selective, ATP competitive PI3Kβ inhibitor and IC50 value is 0.01 μm. Meanwhile, AZD6482 also inhibited insulin-induced human adipocyte glucose uptake in vitro and IC50 value is 4.4 μm. In May 2008, AstraZeneca completed a phase I trial in Thrombosis in Sweden. In Jul 2010, Phase-I for Thrombosis in Sweden was discontinued.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1173900-37-2 |
| Pricing | Inquire |
| Cas | 1173900-37-2 |
| Molecular Weight | 408.46 |
| Molecular Formula | C22H24N4O4 |
| Canonical SMILES | CC1=CN2C(=O)C=C(N=C2C(=C1)[C@@H](C)NC3=CC=CC=C3C(=O)O)N4CCOCC4 |