Nebentan potassium

Nebentan potassium, a potent, selective and orally active non-peptide endothelin ETA receptor antagonist produced by modification of Bosenan, inhibits the binding of [125I] endothelin-1 to cloned human endothelin ETA and ETB receptors with Kis of 0.697 and 569 nM, respectively. It can improve the progression of cor pulmonale and myocardial infarction in vivo.

• Supplier: BOC Sciences
• Product #: 342005-82-7
• Cas: 342005-82-7
• Molecular Weight: 529.61
• Molecular Formula: C24H20KN5O5S
• Canonical SMILES: COC1=CC=CC=C1OC2=C(N=C(N=C2OC)C3=NC=CC=N3)[N-]S(=O)(=O)C=CC4=CC=CC=C4.[K+]