Y-27632 dihydrochloride

Supplier MedChemExpress
Product # HY-10583-50 mg
CAS # 129830-38-2
Pricing 50 mg, USD $210.0
Biological Activity Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride induces apoptosis. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4].
Purity ≥98.0%
MWt 320.26
Formula C₁₄H₂₃Cl₂N₃O
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