Vilazodone hydrochloride
Vilazodone is a serotonergic antidepressant. Vilazodone was approved by the FDA for use in the United States to treat major depressive disorder in 2011. The mechanism of the antidepressant effect of vilazodone is not fully understood but is thought to be related to its enhancement of serotonergic activity in the CNS through selective inhibition of serotonin reuptake. Vilazodone is also a partial agonist at serotonergic 5-HT1A receptors; however, the net result of this action on serotonergic transmission and its role in vilazodone's antidepressant effect are unknown.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1221 |
| CAS # | 163521-08-2 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | EMB-68843; EMB68843; EMB68843; Vilazodone hydrochloride; Viibryd |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H28ClN5O2 |
| Molecular Weight | 477.99 |
| Elemental Analysis | C, 65.33; H, 5.90; Cl, 7.42; N, 14.65; O, 6.69 |
| IUPAC/Chemical Name | 5-(4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl)benzofuran-2-carboxamide, hydrochloride |
| InChi Key | RPZBRGFNBNQSOP-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C26H27N5O2.ClH/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32;/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32);1H |
| SMILES Code | O=C(C1=CC2=CC(N3CCN(CCCCC4=CNC5=C4C=C(C#N)C=C5)CC3)=CC=C2O1)N.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO. |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |