Kenpaullone

Supplier MedChemExpress
Product # HY-12302-10 mg
CAS # 142273-20-9
Pricing 10 mg, USD $108.0
Biological Activity Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC50s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro.
Synonyms 9-Bromopaullone; NSC-664704
MWt 327.18
Formula C₁₆H₁₁BrN₂O
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