Recombinant Human SIRPA protein, Fc-Avi-tagged, Biotinylated

Signal regulatory protein α(SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. Cancer cells highly expressed CD47 that activate SIRPα and inhibit macrophagemediated destruction.

• Supplier: Creative Biomart
• Product #: SIRPA-324HB