Pipamperone HCl
Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even higher in the case of the 5-HT2A receptor), being regarded as "highly selective" for the former two sites at low doses. Pipamperone has low and likely insignificant affinity for the H1 and mACh receptors, as well as for other serotonin and dopamine receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1661 |
| CAS # | 2448-68-2 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Pipamperone, carpiperone; floropipamide; fluoropipamide, floropipamide hydrochloride; R4050, R-4050; R 4050; McN-JR-3345; Brand name: Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H32Cl2FN3O2 |
| Exact Mass | 447.1856 |
| Molecular Weight | 448.4044 |
| Elemental Analysis | C, 56.25; H, 7.19; Cl, 15.81; F, 4.24; N, 9.37; O, 7.14 |
| IUPAC/Chemical Name | 1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride |
| InChi Key | BMXXSXQVMCXGJM-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H |
| SMILES Code | O=C(C1(N2CCCCC2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)N.[H]Cl.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |