Leukotriene A4 Hydrolase from Human, Recombinant
Leukotriene A4 Hydrolase human (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into Leukotriene B4, and also demonstrates aminopeptidase activity. Leukotriene B4 is a lipid chemoattractant that plays critical roles in inflammaton, immune responses, host defenses against infections, and lipid homeostasis. Inhibition of LTA4H in a mouse model decreases LTB4 in the airways and attenuates airway inflammation and airway hyperreactivity through modulation of T cell and dendritic cell function.
| Supplier | Creative Enzymes |
|---|---|
| Product # | NATE-0419 |
| Pricing | 100 ug, contact supplier for pricing |
| CAS | 90119-07-6 |