L-745870 hydrochloride

Supplier MedChemExpress
Product # HY-14325B-10 mM * 1 mL
CAS # 1173023-36-3
Pricing 10 mM * 1 mL, USD $66.0
Biological Activity L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3].
Purity 99.88%
MWt 363.28
Formula C₁₈H₂₀Cl₂N₄
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