L-745870 hydrochloride
Supplier | MedChemExpress |
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Product # | HY-14325B-10 mM * 1 mL |
CAS # | 1173023-36-3 |
Pricing | 10 mM * 1 mL, USD $66.0 |
Biological Activity | L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3]. |
Purity | 99.88% |
MWt | 363.28 |
Formula | C₁₈H₂₀Cl₂N₄ |