PF-4455242 HCl
PF-4455242 is a selective, short-acting antagonist of the κ-opioid receptor. It was pursued in a phase I clinical trial for the treatment of bipolar disorder, and was also investigated as a treatment for depression and substance abuse.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD594 |
| CAS # | 1322001-35-3 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | PF-4455242; PF 4455242; PF4455242; PF-04455242; PF 04455242; PF04455242; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H29ClN2O2S |
| Exact Mass | 408.1638 |
| Molecular Weight | 408.99 |
| Elemental Analysis | C, 61.67; H, 7.15; Cl, 8.67; N, 6.85; O, 7.82; S, 7.84 |
| IUPAC/Chemical Name | (1,1'-Biphenyl)-4-methanamine, N-(2-methylpropyl)-2'-(1-pyrrolidinylsulfonyl)-, hydrochloride (1:1) |
| InChi Key | WRNZYMZEVIVCFL-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C21H28N2O2S.ClH/c1-17(2)15-22-16-18-9-11-19(12-10-18)20-7-3-4-8-21(20)26(24,25)23-13-5-6-14-23;/h3-4,7-12,17,22H,5-6,13-16H2,1-2H3;1H |
| SMILES Code | O=S(C1=CC=CC=C1C2=CC=C(CNCC(C)C)C=C2)(N3CCCC3)=O.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |