Human recombinant UCHL1
PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Recombinant PGP9.5 protein was expressed in E.Coliand purified by using conventional chromatography techniques.
| Supplier | CD BioSciences |
|---|---|
| Product # | APE-040 |
| Pricing | 100 μg, Inquire |
| Product Category | Proteins/Enzymes |
| Gene ID | 7345 |
| Alternate Name | Ubiquitin carboxyl-terminal esterase L1, UCHL1, PARK5, Uch-L1, PGP9.5. |
| Molecular Weight | 24.8 kDa |
| Appearance | Liquid |
| Storage Conditions | -20°C |
| Gene Symbol | UCHL1 |
| Source | E. coli |
| Physical Form Description | 1 mg/mL solution in In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA. |
| Purity by SDS-PAGE | ≥95% |
| Amino Acid Sequence | MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA |