C57BL/6J-Ltaem1 Mouse
The Lta gene (Ensembl: ENSMUSG00000024402) is located on mouse chromosome 17. Four exons are identified, with the ATG start codon in exon 2 and the TAG stop codon in exon 4. Exon 2~4 will be selected as target site. Cas9 and gRNA will be co-injected into fertilized eggs for KO mouse production.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | DMM-001185 |
| Pricing | Inquiry |
| Synonyms | LT, Ltx, Tnfb, LT[a], LT-[a], TNFSF1, Tnlg1e, hlb382, LTalpha, Tnfsf1b, LT-alpha, TNF-beta |
| Category | Mouse Models |
| disease type | T1DM |
| Strain Name | C57BL/6J-Ltaem1 |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Lymphatic system; leprosy type 4; myocardial infarction; Non-Hodgkin's lymphoma; and psoriatic arthritis and other related diseases. |
| Target Name | Lta |
| Gene ID | 16992 |