Simvastatin acid ammonium
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-119695A-10 mM * 1 mL |
| CAS # | 139893-43-9 |
| Pricing | 10 mM * 1 mL, USD $550.0 |
| Synonyms | Tenivastatin ammonium |
| MWt | 453.61 |
| Formula | C₂₅H₄₃NO₆ |
| Biological Activity | Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1]. |
| Purity | 99.32% |