Phrixotoxin 3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-P1218 |
| CAS # | 880886-00-0 |
| Pricing | inquire |
| Biological Activity | Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current[1]. |
| MWt | 4059.72 |
| Formula | C₁₇₆H₂₆₉N₅₁O₄₈S₆ |