Human Proteasome Subunit Alpha Type 7 (PSMA7) Protein
Proteasome Subunit Alpha Type 7 (PSMA7) is a recombinant enzyme. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx073064-50UG |
| Pricing | 50 µg USD $377.0 |
| Host | E. coli |
| Tested Applications | SDS-PAGE |
| UniProt Primary AC | O14818 |
| Activity | Not tested |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
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