TG 100801 Hydrochloride

• Supplier: MedChemExpress
• Product #: HY-10187
• CAS #: 1018069-81-2
• Biological Activity: TG 100801 Hydrochloride is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.
• MWt: 616.54
• Formula: C₃₃H₃₁Cl₂N₅O₃