Immunoglobulin (anti-A, anti-B antibodies test) positive control

This material is a reference preparation for standardising haemagglutination tests performed to control the levels of anti-A and anti B in normal intravenous immunoglobulin (IVIG) products, and ensuring that such tests are sufficiently sensitive and specific. The study showed that the anti-A and anti-B titres for the Positive control preparation were mostly in the 2-fold ranges of 32-64 and 16-32, respectively, using direct haemagglutination of papain-treated A1 and B red cells. These titres should be used as a guide for operators establishing and performing the direct method for anti-A and anti-B. Operators should investigate their assay conditions and reagents in the event of significantly different results being obtained with the Positive control. This preparation may also be used in the IAGT, in which case operators should determine their own titres for assay validity and consistency. IVIG products with anti-A and/or anti-B titres that are higher than those obtained with the Positive control preparation should be compared with the 'Anti-A and anti-B in IVIG: THP-0108-310, using the direct method. Our IVIG Negative Control reference preparation(THP-0108-AB) is suitable for use as a negative control with THP-0108+AB.

• Supplier: Creative Biomart
• Product #: THP-0108+AB