PF-5274857 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13459A |
| CAS # | 1613439-62-5 |
| Pricing | inquire |
| Biological Activity | PF-5274857 hydrochloride is a potent, selective, orally active and brain-penetrant antagonist of Smo, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 hydrochloride has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway[1]. |
| MWt | 473.42 |
| Formula | C₂₀H₂₆Cl₂N₄O₃S |