Afuco™ Anti-Human TNFSF9 ADCC Therapeutic Antibody (PF-05082566), ADCC Enhanced
Anti-TNFSF9 ADCC Enhanced Antibody (PF-05082566) is an ADCC enhanced antibody produced by our Afuco™ platform. PF-05082566 is a fully human IgG2 that binds to the extracellular domain of human 4-1BB with high affinity and specificity. In preclinical studies, this agonist antibody demonstrated its ability to activate NF-κB and induce downstream cytokine production, promote leukocyte proliferation, and inhibit tumor growth in a human PBMC xenograft tumor model. The mechanism of action and robust anti-tumor efficacy of PF-05082566 support its clinical development for the treatment of a broad spectrum of human malignancies.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-618CL |
| Pricing | Inquiry |
| Host | Human |
| Target | TNFSF9 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Applications | FC, Activ, FuncS |
| Storage | Store at -20°C. Open under aseptic conditions. |