Evodiamine
d-Evodiamine is a topoisomerase I and II inhibitor found in the fruit of Evodia rutaecarpa Bentham (Rutaceae). It displays a wide variety of biological activities, including enhancing TRAIL-induced apoptosis in bladder cancer cells, inducing cell cycle arrest in leukemia cells, improving glucose tolerance, and inhibiting viral replication of influenza virus.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD818 |
| CAS # | 518-17-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Evodiamine; Q-100579; Q100579; Q 100579; SC-16015; SC16015; SC 16015 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H17N3O |
| Exact Mass | 303.1372 |
| Molecular Weight | 303.36 |
| Elemental Analysis | C, 75.23; H, 5.65; N, 13.85; O, 5.27 |
| IUPAC/Chemical Name | (S)-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one |
| InChi Key | TXDUTHBFYKGSAH-SFHVURJKSA-N |
| InChi Code | InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1 |
| SMILES Code | O=C1N2[C@](C(NC3=C4C=CC=C3)=C4CC2)([H])N(C)C5=C1C=CC=C5 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |