E2508
E2508 is a selective corticotropin-releasing factor 1 receptor antagonist. E2508 has the potential to be an effective therapy for the treatment of irritable bowel syndrome with a lower risk of adverse events such as constipation compared with the current clinically used 5-HT3 receptor antagonist.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD814 |
| CAS # | 685886-34-4 |
| Pricing | Customizable size, Inquiry |
| Synonym | E2508; E-2508; E 2508; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C36H47N3O7S |
| Exact Mass | 665.3135 |
| Molecular Weight | 665.85 |
| Elemental Analysis | Chemical Formula: C36H47N3O7S Exact Mass: 665.3135 Molecular Weight: 665.8460 Elemental Analysis: C, 64.94; H, 7.12; N, 6.31; O, 16.82; S, 4.81 |
| IUPAC/Chemical Name | N-(Cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine Tosylate |
| InChi Key | NOWKXPVUFWKFHF-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C29H39N3O4.C7H8O3S/c1-5-23-29(31(17-20-9-10-20)18-21-11-13-36-14-12-21)25-8-6-7-24(32(25)30-23)28-26(34-3)15-22(19-33-2)16-27(28)35-4;1-6-2-4-7(5-3-6)11(8,9)10/h6-8,15-16,20-21H,5,9-14,17-19H2,1-4H3;2-5H,1H3,(H,8,9,10) |
| SMILES Code | CCC1=NN2C(C3=C(OC)C=C(COC)C=C3OC)=CC=CC2=C1N(CC4CC4)CC5CCOCC5.OS(=O)(C6=CC=C(C)C=C6)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |