Rapamycin-d3
Supplier | MedChemExpress |
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Product # | HY-10219S |
CAS # | 392711-19-2 |
Pricing | inquire |
Biological Activity | Rapamycin-d3 (Sirolimus-d3) is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2]. |
Synonyms | Sirolimus-d3; AY-22989-d3 |
MWt | 917.19 |
Formula | C₅₁H₇₆D₃NO₁₃ |