Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Antibody
CTLA4 Antibody is a Rabbit Polyclonal antibody against CTLA4. This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
Supplier | Abbexa Ltd. |
---|---|
Product # | abx001680-20UL |
Pricing | 20 µl USD $203.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | WB, IHC |
UniProt Primary AC | P16410 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |