| Supplier |
Creative Peptides |
| Product # |
R1193 |
| CAS # |
107761-42-2 |
| Pricing |
Inquire
|
| Synonyms |
β-Amyloid (1-42), human
|
| MolecularFormula |
C203H311N55O60S
|
| MolecularWeight |
4514.04
|
| Sequence |
- One Letter Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
- Three Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-GIn-L ys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-lle-lle-Gly-Leu-Met-Val-Gly-Gly-Val-Val-lle-Ala
|
| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
| Explanation |
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
|
| Solubility |
Soluble to 1 mg/ml in 50mM Tris buffer
|
| BiologicalActivity |
Human form of the predominant amyloid β-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic.
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