Afuco™ Anti-ERBB3 ADCC Therapeutic Antibody (Elgemtumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ERBB3. Elgemtumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, head and neck. It binds to and locks HER3 in the inactive conformation and does not interfere with its interaction with neuregulin (NRG). The inactivated form of HER3 blocks the PI3K/Akt signaling pathway, thereby inhibiting cellular proliferation in HER2 or NRG expressing tumor cells.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-TAB-422CQ |
| Pricing | Inquiry |
| Host | Human |
| Target | ERBB3 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Applications | ELISA, IHC, FC, IP, IF, BL |
| Storage | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |