Fas-activated serine/threonine kinase

This enzyme is activated during Fas-mediated apoptosis. Following Fas ligation, the enzyme, which is constitutively phosphorylated, is dephosphorylated, and it is the dephosphorylated form that causes phosphorylation of TIA-1, a nuclear RNA-binding protein. Phosphorylation of TIA-1 precedes the onset of DNA fragmentation.

• Supplier: Creative Enzymes
• Product #: EXWM-3159
• CAS: 170347-50-9