Sunitinib Malate
Supplier | MedChemExpress |
---|---|
Product # | HY-10255-100 mg |
CAS # | 341031-54-7 |
Pricing | 100 mg, USD $60.0 |
Synonyms | SU 11248 Malate |
MWt | 532.56 |
Formula | C₂₆H₃₃FN₄O₇ |
Biological Activity | Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. |
Purity | ≥99.0% |