Fenretinide (4-HPR, (4-Hydroxyphenyl)retinamide, all-trans--N-(4-Hydroxyphenyl)retinamide, N-(4-Hydroxyphenyl)-all-trans--retinamide, N-(4-Hydroxyphenyl)retinamide, all-trans--4'-Hydroxyretinanilide, McN-R-1967, MK-4016, Retinoic acid p-hydroxyphenylamide, Retinoic acid p-hydroxyanilide, RII retinamide, Ro 22-4667, CAS 65646-68-6), >99%

LC Laboratories' Product Number F-4077 - Fenretinide (4-HPR, (4-Hydroxyphenyl)retinamide, all-trans--N-(4-Hydroxyphenyl)retinamide, N-(4-Hydroxyphenyl)-all-trans--retinamide, N-(4-Hydroxyphenyl)retinamide, all-trans--4'-Hydroxyretinanilide, McN-R-1967, MK-4016, Retinoic acid p-hydroxyphenylamide, Retinoic acid p-hydroxyanilide, RII retinamide, Ro 22-4667, CAS 65646-68-6), >99% - for research use only. Fenretinide is a vitamin A analogue and has been used as a chemopreventive retinoid for women at risk of developing contralateral breast cancer. Fenretinide treatment resulted in a significant risk reduction of second breast cancer in premenopausal women after 15 year followups, which is remarkable at younger ages, and persisted several years after treatment cessation. Fenretinide is concentrated by breast tissue in patients. The mechanism of action for fenretinide is not yet fully understood. It may inhibit cell growth through induction of apoptosis, not differentiation, and through vitamin A receptor-dependent and -independent mechanisms. Another CAS number previously assigned to Fenretinide, namely 1006055-28-2, has been deleted by CAS and is no longer in use.

• Supplier: LC Laboratories
• Product #: F-4077
• Sku #: F-4077_2g