| Supplier |
Ace Therapeutics |
| Product # |
NSC953 |
| Pricing |
Inquiry
|
| Product Size |
100 µg
|
| Purity |
> 85 % as determined by SDS-PAGE
|
| Product Type |
Proteins
|
| Synonyms |
ARIA Protein, Human; GGF Protein, Human; GGF2 Protein, Human; HGL Protein, Human; HRG Protein, Human; HRG1 Protein, Human; HRGA Protein, Human; MST131 Protein, Human; MSTP131 Protein, Human; NDF Protein, Human; Neuregulin 1 Protein, Human; NRG1-IT2 Protein, Human; SMDF Protein, Human
|
| Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method
|
| Activity |
- 1. Immobilized Human ERBB3 His at 2 μg/ml (100 μl/well) can bind Human NRG1 Fc, the EC50 of Human NRG1 Fc is 8-40 ng/mL.
- 2. Immobilized Rhesus ERBB3 His at 2 μg/ml (100 μl/well) can bind Human NRG1 Fc, the EC50 of Human NRG1 Fc is 20-80 ng/mL.
|
| Protein Construction |
A DNA sequence encoding the N-terminal fragment (Ser 2-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was fused with the Fc region of human IgG1 at the N-terminus.
|
| Accession# |
Q02297-6
|
| Expressed Host |
HEK293 Cells
|
| Species |
Human
|
| Predicted N Terminal |
Glu
|
| Molecule Mass |
The recombinant human NRG1（aa2-246）/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 505 amino acids and has a calculated molecular mass of 55.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 75 kDa due to glycosylation.
|
| Formulation |
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
|
| Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
|
| Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Reconstitution |
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
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