Wax, Yellow
Yellow or light brown pieces or plates with a fine-grained matt, noncrystalline fracture and a faint characteristic odor. The wax becomes soft and pliable when warmed.
| Supplier | CD Formulation |
|---|---|
| Product # | PE-0601 |
| Pricing | , Inquire for price |
| product1 | Other Materials |
| Applications | Yellow wax is used in food, cosmetics, and confectionery products.Its main use is in topical pharmaceutical formulations, where it is used at a concentration of 5-20%, as a stiffening agent in ointments and creams. Yellow wax is also employed in emulsions because it enables water to be incorporated into water-in-oil emulsions. In some oral formulations yellow wax is used as a polishing agent for sugar-coated tablets. It is also used in sustained-release formulations. Yellow wax coatings can be used to affect the release rate of drug from ion-exchange resin beads, and yellow wax has also been used in multiparticulate controlled-release dosage forms of chlorphenamine maleate. Yellow wax forms a soap with borax. |
| Safety | Yellow wax is generally regarded as an essentially nontoxic and nonirritant material, and is used in both topical and oral formulations. However, hypersensitivity reactions attributed to contaminants in the wax, although rare, have been reported. |
| Incompatibilities | Incompatible with oxidizing agents. |
| Synonyms | Apifil; cera flava; E901; refined wax |
| CAS Number | 8012-89-3 |
| Category | Controlled-release Agents; Polishing Agents; Stabilizing Agents; Stiffening Agents |
| UNII | 2ZA36H0S2V |
| Chemical Name | Yellow beeswax |
| Grade | Pharmceutical Excipients |
| Administration route | Oral and topical |
| Dosage Form | Oral capsules and tablets, and topical preparations |
| Stability and Storage Conditions | When the wax is heated above 150℃ esterification occurs with a consequent lowering of acid value and elevation of melting point. Yellow wax is stable when stored in a well-closed container, protected from light. |
| Source and Preparation | Yellow wax is a natural secretion of bees and is obtained commercially from honeycombs. Honey is abstracted from combs either by draining or centrifugation, and water is added to the remaining wax to remove soluble impurities. Hot water is then added to form a floating melt, which is strained to remove foreign matter. The wax is then poured into flat dishes or molds to cool and harden. |