Withaferin A (WFA)
Withaferin A (WFA) potently inhibits NF-κB activation by preventing the tumor necrosis factor-induced activation of IκB kinase β via a thioalkylation-sensitive redox mechanism. Withaferin A binds to the intermediate filament (IF) protein, vimentin with antitumor and antiangiogenesis activity. Withaferin A is a steroidal lactone isolated from Withania somnifera.
Supplier | Selleck Chemicals |
---|---|
Product # | S8587 |
Sku # | S8587-1mg |
Pricing | 1mg, $127.00 |