Pentetic Acid
Pentetic acid occurs as a white crystalline solid and is almost odorless.
| Supplier | CD Formulation |
|---|---|
| Product # | PE-0616 |
| Pricing | , Inquire for price |
| product1 | Other Materials |
| Molecular Formula | C14H23N3O10 |
| Molecular Weight | 393.35 |
| Applications | Pentetic acid is mainly used as a chelating agent in the preparation of imaging and contrast agents for radionuclide and magnetic resonance imaging. It is also used as a carrier excipient for neutron-capture isotopes in, for example, radiotherapy. Pentetic acid-isotope complexes have also been considered as model active substances in scintigraphic imaging studies. Pentetic acid has been used to chelate metal ions to reduce formation of reactive oxygen species during lyophilization. |
| Safety | Pentetic acid is used in intrathecal and intravenous injection preparations. The pure form of pentetic acid is moderately toxic by the intraperitoneal route. LD50 (mouse, IP): 0.54 g/kg LD50 (mouse, oral): 4.84 g/kg |
| Incompatibilities | The activity of pentetic acid as a chelating agent may cause unwanted effects in formulations containing metal ions. The desired chelate may be displaced by other ions from the formulation. |
| Synonyms | Acidicum penteticum; N, N-bis[2-[bis(carboxymethyl)amino]ethyl]- glycine; [[(carboxymethyl)imino]bis(ethylenenitrilo)]tetraacetic acid; diethylenetriamine pentaacetic acid; diethylenetriamine- N, N, N 0 , N 0 , N 00 -pentaacetic acid; (diethylenetrinitrilo)pentaacetic acid; DTPA; glycine, N, N-bis[2-[bis(carboxymethyl)amino]ethyl]; pentacarboxymethyl diethylenetriamine; Versenex; ZK-43649 |
| CAS Number | 67-43-6 |
| Category | Antimicrobial Preservative; Chelating Agents; Sequestering Agents; Stabilizing Agents |
| UNII | 7A314HQM0I |
| Chemical Name | 2-[Bis[2-(bis(carboxymethyl)amino)ethyl]amino]acetic acid |
| Grade | Pharmceutical Excipients |
| Administration route | Intrathecal and intravenous |
| Dosage Form | Intrathecal and intravenous injections |
| Stability and Storage Conditions | Pentetic acid should be stored in well-closed containers in a cool, dry place. |
| Source and Preparation | Pentetic acid is a pentaacetic acid triamine formed during the preparation of the amino carboxylic acid and its salt. |