| Supplier |
Creative Peptides |
| Product # |
10-101-01 |
| CAS # |
16960-16-0 |
| Pricing |
Inquire
|
| Synonyms |
Cosyntropin; Tetracosactrin; α1-24-Corticotropin; ACTH(1-24); 1-24-ACTH; 1-24-Corticotropin; ACTH 1-24; ACTH1-24; Cortosyn; Cortrosyn; Tetracosactide; Tetracosapeptide; ACTH (1-24); Tetracosactid; Tetracosactide; Cortrosinta; Actholain; Cortrosyn; Synacthen; Nuvacthen depot; Cortrophin S
|
| MolecularFormula |
C136H210N40O31S
|
| MolecularWeight |
2933.5
|
| Sequence |
- One Letter Code: SYSMEHFRWGKPVGKKRRPVKVYP
- Three Letter Code: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
|
| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
| Explanation |
Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
|
| Application |
Tetracosactide is used for diagnostic purposes. It is suitable for treatment of adrenal insufficiency of central origin. It can also be used to diagnose Addison's disease.
|
| Activity |
Agonist
|
| Solubility |
H2O : 100 mg/mL (34.09 mM; Need ultrasonic)
|
| Target |
Adrenocorticotropic hormone receptor
|