Ribociclib
Ribociclib is an orally available, and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM. Phase 3.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7440 |
| Sku # | S7440-5mg |
| Pricing | 5mg, $79.00 |
Citations for this product:
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bioRxiv - Systems Biology 2020Quote: ... Cells were continuously treated with ribociclib (Selleck Chemicals, Cat. No: S7440) at 1µM concentration for 1 month followed by 250 nM for 4 months to develop resistance ...
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bioRxiv - Cell Biology 2019Quote: ... CDK4/6 inhibitor LEE011 (Ribociclib) at 9μM (Selleck Chemicals S7440), and CDK1/2 inhibitor CAS 443798-55-8 at 3μM (EMD Biosciences #217714).
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bioRxiv - Systems Biology 2022Quote: ... cells were cultured and continuously treated with ribociclib (Selleck Chemicals, Cat. No: S7440) at 1µM for 1 month ...
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bioRxiv - Systems Biology 2022Quote: ... Spheroids were treated with the following drug therapies at specified doses described in results and figures 1 and 4: ribociclib (Selleck Chemicals, Cat. No: S7440), estradiol (Peprotech ...