| Supplier |
Creative Peptides |
| Product # |
R1853 |
| CAS # |
141801-26-5 |
| Pricing |
Inquire
|
| MolecularFormula |
C32H37N5O5
|
| MolecularWeight |
571.7
|
| Sequence |
- One Letter Code: YPFF (Modifications: Phe-3 = C-terminal amide)
- Three Letter Code: H-Tyr-Pro-Phe-Phe-NH2
|
| ShippingCondition |
Evaluation sample solution : ship with blue ice; All other available size: ship with RT , or blue ice upon request
|
| Explanation |
Endomorphin-2 is a peptide amide with the highest known affinity and specificity for the mu-opioid receptor.
|
| ChemicalName |
(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
|
| Activity |
Endogenous peptide with extremely high affinity and selectivity for μ-opioid receptors (with Ki values of 0.69, 9233 and 5240 nM for μ, δ and κ respectively).
|
| InChI |
InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1
|
| InChIKey |
XIJHWXXXIMEHKW-LJWNLINESA-N
|
| CanonicalSMILES |
C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N
|
| Solubility |
Soluble to 0.40 mg/ml in water
|
| IsomericSMILES |
C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N
|
| Purity |
> 95%
|