Antigen Peptide Transporter 2 (TAP2) Antibody
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].
Supplier | Abbexa Ltd. |
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Product # | abx001354-20UL |
Pricing | 20 µl USD $203.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | WB, IHC, IF/ICC |
UniProt Primary AC | Q03519 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |