Mouse Anti-HLA-A2 Recombinant Antibody (clone G1); scFv Fragment
A recombinant Ab that exhibits a characteristic TCR-like binding specificity, yet, unlike TCRs, it did so with a high affinity in the nanomolar range. The TCR-like Ab can recognize the native MHC-peptide complex expressed on the surface of APCs, and on peptide-pulsed or native melanoma cells. Moreover, when fused to a very potent cytotoxic effector molecule in the form of a truncated bacterial toxin, it was able to specifically kill APCs in a peptide-dependent manner.
| Supplier | Creative Biolabs |
|---|---|
| Product # | FAMAB-0167-YC-S(P) |
| Pricing | Inquiry |
| Host | Mouse |
| Target | HLA-A2 |
| Species Reactivity | Human |
| Type | Mouse scFv |
| Applications | ELISA, FC, IHC, Cyt |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |